Understanding the Role of Botulinum Toxin A in the Treatment of the Overactive Bladder—More than Just Muscle Relaxation
نویسندگان
چکیده
Apostolos Apostolidis *, Axel Haferkamp , K. Roger Aoki c a Institute of Neurology and Department of Uro-Neurology, The National Hospital for Neurology and Neurosurgery, London, United Kingdom Department of Urology, University of Heidelberg, Heidelberg, Germany Neurotoxins Research Program, Discovery Research, Biological Sciences, Allergan Inc, USA e u r o p e a n u r o l o g y s u p p l e m e n t s 5 ( 2 0 0 6 ) 6 7 0 – 6 7 8
منابع مشابه
Histopathologic Changes of Extraocular Mus-cle Fibers after Injection of Botulinum Toxin
Background: Use of botulinum toxin is becoming a popular way in treatment of some forms of strabismus.To evaluate the morphological changes in the orbital surface layer muscles of the rabbit eye following a single injection of botulinum toxin. Methods: 10 white Dutch rabbits weighing 2–3 kg received either 10 units (group 1; n=5) or 20 units (group 2; n=5) of botulinum toxin into the superior r...
متن کاملسم بوتولینوم- A در درمان بیاختیاری ادراری ناشی از مثانه بیشفعال به دنبال ترومای نخاعی
Background: We evaluated the efficacy of botulinum-A toxin (BTX-A) injection into detrusor muscle in patients with incontinence resistant to anticholinergic drugs due to detrusor overactivity.Methods: Our prospective study included 12 male patients with detrusor overactivity and incontinence due to spinal cord injury, which had been unsuccessfully treated with anticholinergic medication. Under ...
متن کامل[Urinary incontinence in women].
Results: There are many diagnostic and therapeutic options, whose use should be based on the degree of the patient’s suffering and on her motivation to be treated. Anticholinergic drugs are of established value in the treatment of overactive bladder. They are used in combination with possible lifestyle changes and bladder training. In some circum-stances, botulinum toxin injections can be consi...
متن کاملBotulinum toxin A for the Treatment of Overactive Bladder
The standard treatment for overactive bladder starts with patient education and behavior therapies, followed by antimuscarinic agents. For patients with urgency urinary incontinence refractory to antimuscarinic therapy, currently both American Urological Association (AUA) and European Association of Urology (EAU) guidelines suggested that intravesical injection of botulinum toxin A should be of...
متن کاملBotulinum toxin-A for the treatment of overactive bladder: UK contributions
BACKGROUND Botulinum toxin-A (BoNT/A) is now established second-line management for refractory overactive bladder (OAB) and recognised in many incontinence guidelines and pathways. For those with neurogenic detrusor overactivity secondary to spinal cord injury or multiple sclerosis, the toxin is currently licensed in certain parts of the world, including the UK. It is an effective treatment in ...
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تاریخ انتشار 2006